5-Aminolevulinic acid promotes arachidonic acid biosynthesis in the red microalga Porphyridium purpureum

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5-Aminolevulinic acid promotes arachidonic acid biosynthesis in the red microalga Porphyridium purpureum

BACKGROUND The microalga Porphyridium purpureum within Rhodophyta abundantly produces several valuable proteins, polysaccharides, pigments and long-chain polyunsaturated fatty acid; it is especially effective in accumulating arachidonic acid (ARA). However, this high ARA yield is always achieved in conditions unfavourable for cell growth. In this study, we present a method for obtaining desirab...

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Genome of the red alga Porphyridium purpureum

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Glutamic Acid-l-semialdehyde, a Hypothetical Intermediate in the Biosynthesis of 5-Aminolevulinic Acid

W hether glutamate-l-sem ialdehyde (G -l-SA ) or 4,5 dioxovalerate (DOVA) is the intermedi­ ate between glutamate and A LA in the C-5 tetrapyrrol pathway is still a matter of controversy. Since no data characterizing G -l-SA are available it is not possible either to identify G -l-SA as intermediate or a precursor of ALA. Therefore, attem pts were made to establish a chemical synthesis of this ...

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ژورنال

عنوان ژورنال: Biotechnology for Biofuels

سال: 2017

ISSN: 1754-6834

DOI: 10.1186/s13068-017-0855-4